This course aims to provide students with knowledge and understanding of the basic concepts of statistics which are widely applied in practice and the use of statistics-based software for research and application in the world of education based on local wisdom. This course examines the meaning and scope of the role of Biostatistics in the Field of Biology Education, Determining the appropriate type of data measurement in obtaining data, Descriptive Statistics, Concepts of inferential statistics, Test selection techniques using parametric and non-parametric statistical analysis techniques, as well as multivariate analysis methods, skills that necessary to utilize IT in analyzing data as well as providing opportunities for data analysts. This course is presented through theory, discussions, assignments, presentations and statistical practice as well as being able to make a proposal for a thesis linked to methods by collecting data, organizing, analyzing data and drawing appropriate conclusions based on data analysis.